A Study to Evaluate Safety and Immunogenicity of mRNA-1273 Vaccine to Prevent COVID-19 in Adult Organ Transplant Recipients and in Healthy Adult Participants
Completed · Phase 3
Conditions studied: SARS-CoV-2
In brief
This is an open-label study to evaluate the safety, reactogenicity, and immunogenicity of mRNA-1273 Severe Acute Respiratory Syndrome coronavirus (SARS-CoV-2) vaccine in adults with a kidney or liver solid organ transplant (SOT) and in healthy adult participants. The primary goal of the study is to evaluate the safety of mRNA-1273 and the serum antibody (Ab) responses obtained 28 days after the last dose of mRNA-1273.
Key facts
- Study ID
- NCT04860297
- Run by
- ModernaTX, Inc.
- People needed
- 234
- Starts
- 2021-04-16
- Expected to finish
- 2023-05-22
- Last updated by the study team
- 2024-06-18
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
Where it is running
- Aventiv Research Inc — Mesa, Arizona, United States
- California Institute of Renal Research — San Diego, California, United States
- Yale University School of Medicine — New Haven, Connecticut, United States
- Tampa General Medical Group — Tampa, Florida, United States
- Piedmont Transplant Institute — Atlanta, Georgia, United States
- Brigham and Women's Hospital — Boston, Massachusetts, United States
- University of Massachusetts Medical School — Worcester, Massachusetts, United States
- University of Nebraska Medical Center — Omaha, Nebraska, United States
- Northwell Health — Manhasset, New York, United States
- Colombia University Medical Center — New York, New York, United States
- University of Cincinnati — Cincinnati, Ohio, United States
- Cleveland Clinic Hospital — Cleveland, Ohio, United States
- Hospital of The University of Pennsylvania — Philadelphia, Pennsylvania, United States
- Rhode Island Hospital — Providence, Rhode Island, United States
- University of Washington Medical Center — Seattle, Washington, United States
Full record on ClinicalTrials.gov
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