Geriatric Anorexia Study

Completed

Conditions studied: Healthy

In brief

Reduction in appetite and/or food intake among older individuals is referred to as anorexia of aging (AOA, also known as Geriatric Anorexia). AOA is linked with myriad comorbidities associated with aging, contributes significantly to adverse health consequences in old age, and has been used as a predictor of morbidity and mortality. The overall aim of this study is to assess the feasibility and burden of the proposed in-laboratory and out-of-laboratory assessments to study Geriatric Anorexia. This will be accomplished with the use of questionnaires as well as devices that evaluate movement, metabolism, body weight composition, glucose levels, and nutritional scale.

Key facts

Study ID: NCT04858932
Run by: Boston University
People needed: 51
Starts: 2021-04-27
Expected to finish: 2021-12-15
Last updated by the study team: 2022-02-01

Who can join

Age: 65 and older, up to 85. Sex: any. Healthy volunteers: accepted.

You may qualify if…

[separated into the three groups based on the Fried Criteria: 0, 1-2, 3 or above]
Male or female participants aged 65 - 85 years.
No clinically significant health problems other than well controlled chronic conditions (e.g., allergies and dermatitis)
No recent hospitalizations/acute events in last 12 months.
No active or recent (within 12 months) cancer diagnosis except skin cancer (limited to only non-complicated Squamous Cell Carcinoma (SCC)/Basal Cell Carcinoma (BCC)).
Body mass index (BMI) < 30 kg/m2
Able to understand and cooperate with study procedures and able to read, understand and provide informed consent. Evidence of a personally signed and dated informed consent document indicating that the participant has been informed of all pertinent aspects of the study
Participants should not have any food aversion which could influence their food selection if standardized meals are used as part of the protocol.
Native English speakers or demonstrated fluency in English as determined by the Investigator.
Wide Range Achievement Test (WRAT-4) Word Reading Subtest equivalent to 8th grade reading level or greater.
Normal or corrected-to-normal vision

You may not qualify if…

Treatment with an investigational drug within 30 days of enrollment
A moderate to severe alcohol use disorder diagnosis within 6 months of the screening as disclosed by the subject
Subjects who are investigational site staff members directly involved in the conduct of the study and their family members, site staff members otherwise supervised by the investigator, or subjects who are Boston University/Boston Medical Center directly involved in the conduct of the study
Inability to comply with study requirements.
Has any clinically significant medical disorder, condition, disease or clinically significant finding at screening that precludes subject's participation in study activities including any self-reported diagnosis of eating disorders.
Participants with electronic implant devices, such as pacemaker.
Non-English Reader as measured by the WRAT-4.

Where it is running

Evans Biomedical Research Center — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.