Periodontal Assessment of a Bariatric Care Population

Recruiting now

Conditions studied: Bariatric Surgery Candidate, Obesity

In brief

Our primary aim is to investigate the prevalence and severity of Periodonotal Disease (PD) in a population of obese patients. Our secondary objectives are to: Investigate inflammatory biomarkers that have been associated with PD in the saliva of obese patients. Investigate the association of FTO gene (Obesity) polymorphisms with the prevalence of PD in this population. Investigate and describe the subgingival microbial flora in obese patients with PD from subgingival dental plaque samples as well as the salivary samples.

Key facts

Study ID

NCT04851470

Run by

Queen Mary University of London

People needed

394

Starts

2014-01-31

Expected to finish

2027-12-31

Last updated by the study team

2026-07-02

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Each subject must meet all of the following inclusion criteria to be enrolled in the study:
• Subject must be over 18 years of age.
• Subject must have a BMI of higher or equal to 30 kg/ m2
• Subject must have voluntarily given written informed consent.

You may not qualify if…

• Subjects meeting any of the following exclusion criteria are not to be enrolled in the study:
• Subject is currently involved in other research involving the use of antibiotics or novel or unknown medications.
• Self-reported pregnancy.
• Subject is on chronic treatment (i.e., two weeks or more) with specific medications known to affect periodontal status (phenytoin or cyclosporine) within one month of baseline visit.
• Subject knowingly has HIV or Viral Hepatitis.
• Patients are completely edentulous.
• Subject with uncontrolled systemic illnesses.
• Subject is not capable to give informed consent.
• Subjects on chronic antibiotic therapy (ie two weeks or more in the previous month).

Where it is running

• Barts Health NHS Trust Dental Hospital — London, United Kingdom (enrolling)
• Centre for Oral Clinical Research (COCR) — London, United Kingdom (enrolling)
• St Bartholomew's Hospital, Barts Health NHS Trust — London, United Kingdom (enrolling)
• Luton and Dunstable University Hospital — Luton, United Kingdom (enrolling)

Full record on ClinicalTrials.gov

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