Dental and Periodontal Status of Patients With Sjögren's Syndrome.

Recruiting now

Conditions studied: Sjögren Syndrome

In brief

Sjögren's syndrome (SS) is a rare chronic systemic autoimmune disease characterized by destruction of the exocrine glands, including the salivary glands.The lack of saliva exposes the patient to dental caries, and dental wear although this has rarely been shown in Sjögren's patients. Moreover, these patients seem to have more inflammation and gingival recession, although this has not been clearly identified in the literature. Our main objective is to assess the prevalence of dental wear and gingival recession in patients with Sjögren's syndrome by analyzing of the Basic Erosive Wear Examination (BEWE) score for erosions, Basic Erosive Wear Abrasion (BEWA) score for attrition and percentage of sites with periodontal recessions greater than 3 mm in relation to the total number of sites. Our secondary objectives are to investigate a correlation between the prevalence of dental and gingival wear, gingival inflammation, Decayed, Missing, and Filled Teeth (DMFT) index and (1) salivary parameters and (2) oral quality of life. The salivary samples will be kept in a biological collection within the URP2496 for later analysis (biological collection CB-SJO).

Key facts

Study ID

NCT04848870

Run by

Assistance Publique - Hôpitaux de Paris

People needed

100

Starts

2022-01-12

Expected to finish

2032-01-12

Last updated by the study team

2024-12-30

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patient with Sjögren Syndrome
• Patient > 18 years old
• Patient affiliated to a social security system, beneficiary or beneficiary of a right other than AME
• Patient who speaks and understands French well enough to be able to read and understand the study information note.
• Patient who does not object to his participation in the study

You may not qualify if…

• Patient having expressed his opposition to participate in the research

Where it is running

• Service de Médecine bucco-dentaire — Ivry-sur-Seine, Île-de-France Region, France (enrolling)

Full record on ClinicalTrials.gov

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