Efficacy and Safety of MB-CART2019.1 vs. SoC in Lymphoma Patients

Recruiting now · Phase 2

Conditions studied: Diffuse Large B-cell Lymphoma

In brief

In the current protocol version, there are two parts. Part I is a pivotal Phase II randomised, multi-centre, open-label study to evaluate the efficacy and safety of MB-CART2019.1 compared to standard of care therapy in participants with relapsed/refractory diffuse large B-cell lymphoma, who are not eligible for high-dose chemotherapy and autologous stem cell transplantation. Part II is a Phase II single-arm, open-label, multi-centre study evaluating the efficacy and safety of MB-CART2019.1 in younger, fit participants with R-R DLBCL. Part II will start after completion of enrolment in Part I.

Key facts

Study ID
NCT04844866
Run by
Miltenyi Biomedicine GmbH
People needed
213
Starts
2021-08-18
Expected to finish
2031-09-30
Last updated by the study team
2026-06-10

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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