A Prognostic Transcriptomic Signature for Chronic Hypersensitivity Pneumonitis

Running, not enrolling

Conditions studied: Hypersensitivity Pneumonitis

In brief

Up to 150 patients with hypersensitivity pneumonitis will be enrolled at 7 clinical centers across the United States. Patients will be followed for 24 months to determine if biomarkers in the blood can predict disease progression.

Key facts

Study ID

NCT04844359

Run by

National Jewish Health

People needed

137

Starts

2021-01-06

Expected to finish

2026-07-31

Last updated by the study team

2026-04-09

Who can join

Age: 18 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of chronic hypersensitivity pneumonitis
• Age 18 through 85 years.
• Diagnosis of chronic hypersensitivity pneumonitis by HRCT
• Able to understand and sign a written informed consent form.
• Able to understand the importance of adherence to the study protocol and willing to follow all study requirements

You may not qualify if…

• Not a suitable candidate for enrollment or unlikely to comply with the requirements of this study
• Known explanation for the interstitial lung disease
• Clinical diagnosis of any connective tissue disease
• Listed or expected to receive a lung transplant within 4 months from enrollment
• Pregnant women

Where it is running

• University of Arizona — Tucson, Arizona, United States
• University of California Davis — Sacramento, California, United States
• National Jewish Health — Denver, Colorado, United States
• University of Chicago — Chicago, Illinois, United States
• Mayo Clinic — Rochester, Minnesota, United States
• University of Texas Southwestern — Dallas, Texas, United States
• University of Utah — Salt Lake City, Utah, United States

Full record on ClinicalTrials.gov

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