LIFT Intervention in Liver Transplant Candidates

Completed · Not applicable

Conditions studied: Frailty, Cirrhosis, Liver Transplant

In brief

Frailty is a significant problem in patients undergoing liver transplant and is associated with poor outcomes and survival. Hence, optimizing physical fitness and counteracting frailty is important. However, many interventions are very resource intensive and therefore not feasible. In this study, the investigators aim to test the effectiveness of a newly designed intervention to improve frailty in liver transplant candidates. The "LIver FrailTy" intervention (LIFT) will consist of an evaluation by a physical therapist, an individualized home exercise prescription (HEP), exercise tracking using a smart phone application, daily text reminders to exercise and recurrent telephone check-ins.

Key facts

Study ID

NCT04836923

Run by

Northwestern University

People needed

81

Starts

2020-10-01

Expected to finish

2024-03-01

Last updated by the study team

2026-05-15

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients with a diagnosis of liver cirrhosis being evaluated for liver transplantation in hepatology/transplant evaluation clinic
• English-speaking
• Patients with access to a smart phone (with videoconference capabilities)
• Vulnerable populations: We will include patients who are cognitively impaired due to hepatic encephalopathy and unable to consent for themselves.

You may not qualify if…

• Patients < 18 years of age
• Patients who require outpatient physical therapy.
• Patients without the ability to consent for themselves or through a medical power of attorney.

Where it is running

• Northwestern Medicine — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

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