The Effect of Upneeq (Oxymetazoline Hydrochloride 0.1%) on Eyelid Position, Eye Redness, and Eye Appearance
Completed · Phase 4 · Has a placebo group
Conditions studied: Ptosis, Eyelid, Conjunctiva Inflamed, Eye Manifestations
In brief
The purpose of the research is to see if Upneeq ( oxymetazoline 0.1% ophthalmic solution) has an effect on eyelid position, eye redness, or patient-perceived appearance of the eyes.
Key facts
- Study ID
- NCT04831047
- Run by
- University of Miami
- People needed
- 114
- Starts
- 2021-06-08
- Expected to finish
- 2022-04-01
- Last updated by the study team
- 2023-04-24
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Adults age 18 and above able to provide informed consent to participate
- Subject with stable ocular health, defined as no ocular conditions requiring ongoing topical therapy or recent surgical intervention
You may not qualify if…
- Adults unable to consent
- Individuals less than 18 years of age
- Prisoners
- Pregnant women.
- Known contradictions or sensitivities to study medication (oxymetazoline)
- Ocular surgery within the past 3 months or refractive surgery within the past six months
- Grossly abnormal lid margins, anatomical abnormalities, previous eyelid or orbital surgery
- Variable ptosis or eyelid position (e.g., myasthenia gravis, thyroid eye disease, or blepharospasm)
- Any ocular or systemic condition that, in the opinion of the investigator, would confound study data, interfere with the subject's study participation, or affected the subject's safety or trial parameters
- Presence of an active ocular infection
- Prior (within 5 days of beginning study treatment) use of eye whiteners (eg, vasoconstrictors), decongestants, antihistamines (including over the counter and herbal topical ophthalmic medications), phenylephrine dilating drops, any other topical ophthalmic agents
- Inability to sit comfortably for 15 - 30 minutes
Where it is running
- University of Miami Bascom Palmer Eye Institute — Miami, Florida, United States
Full record on ClinicalTrials.gov
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