Systemic Lidocaine Versus Ultrasound-guided Adductor Canal Block for Patients Undergoing Total Knee Arthroplasty

Completed · Phase 4

Conditions studied: Arthroplasty, Replacement, Knee, Total Knee Arthroplasty

In brief

The investigators are evaluating the postoperative outcomes in patients undergoing total knee arthroplasty that receive either systemic lidocaine or ultrasound-guided adductor canal block as part of their anesthetic plan.

Key facts

Study ID

NCT04828083

Run by

Rhode Island Hospital

People needed

120

Starts

2021-03-01

Expected to finish

2024-09-02

Last updated by the study team

2026-06-15

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• ASA PS 1-3 patients undergoing primary, unilateral total knee arthroplasty

You may not qualify if…

• ASA PS classification of 4 or greater
• Pre-existing neuropathy
• Coagulopathy
• Chronic opioid consumption (>3 months)
• Infection at the site
• Known allergy to study medications (lidocaine)
• High grade atrioventricular block (cardiac conduction system impairment)
• A history of CVA/TIA
• Currently using lidocaine patches
• Known liver disease

Where it is running

• Rhode Island Hospital — Providence, Rhode Island, United States

Full record on ClinicalTrials.gov

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