The Pediatric ALL Evaluation and Trial

Recruiting now · Not applicable

Conditions studied: ACL Injury, ACL Tear

In brief

The overall aim of this multicenter RCT is to determine whether concomitant ALL reconstruction in children undergoing and ACL reconstruction will longitudinally result in a lower rate of graft failure than ACL reconstruction alone.

Key facts

Study ID

NCT04825587

Run by

Ann & Robert H Lurie Children's Hospital of Chicago

People needed

240

Starts

2021-04-28

Expected to finish

2030-04-01

Last updated by the study team

2026-05-29

Who can join

Age: any, up to 18. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age 18 and under
• Surgery within 6 months of injury
• Undergoing primary ACL reconstruction without previous injury or surgery
• Quadriceps tendon autograft ACL reconstruction
• Closing or closed physes

You may not qualify if…

• Over 18 years old
• Previous ipsilateral knee injury or surgery
• Neuromuscular or developmental disorders affecting knee anatomy, cognition, or neuromuscular control
• Other concomitant ligament reconstruction aside from the ALL (i.e., MCL, PCL, PLC)
• Revision ACL reconstruction
• ACL reconstruction with graft other than quadriceps tendon
• IT band (modified MacIntosh) ACL reconstruction
• A cartilage lesion requiring anything more than debridement
• Open physes requiring both femoral and tibial physeal-sparing technique

Where it is running

• Lurie Children's Hospital — Chicago, Illinois, United States (enrolling)

Full record on ClinicalTrials.gov

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