Exercise Capacity According to Coronary Microvascular Dysfunction and Body Composition
Recruiting now · Not applicable
Conditions studied: Heart Failure With Preserved Ejection Fraction (HFpEF)
In brief
The correlation of coronary microvascular function and body composition with cardiopulmonary exercise capacity will be assessed in patients with heart failure with preserved ejection fraction.
Key facts
- Study ID
- NCT04822649
- Run by
- Korea University Anam Hospital
- People needed
- 100
- Starts
- 2021-04-15
- Expected to finish
- 2025-12-31
- Last updated by the study team
- 2025-09-02
Who can join
Age: 20 and older, up to 80. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age 20 to 80
- Typical/atypical chest pain or ischemic symptoms including dyspnea
- No significant coronary artery stenosis (>50% stenosis) in coronary angiography or computed tomography
- Left ventricular ejection fraction ≥50%
You may not qualify if…
- More than moderate valvular heart disease
- Congenital heart disease
- Chronic renal failure (estimated glomerular filtration rate <30 ml/min/1.73m2) or end-stage renal failure undergoing hemodialysis or peritoneal dialysis
- Asthma, chronic obstructive pulmonary disease and primary pulmonary hypertension
- Receiving anticancer drugs
- Vasculitis associated with autoimmune diseases
- Patients with difficulty in performing exercise load evaluation (treadmill, bicycle ergometer)
- Atrial fibrillation
- Atrioventricular block with more than second degrees, symptomatic bradycardia, cryo-node failure syndrome, Wolff-Parkinson-White (WPW) patients
Where it is running
- Korea University Anam Hospital — Seoul, South Korea (enrolling)
Full record on ClinicalTrials.gov
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