Physical Inactivity Impacts on Blood Vessel Health and Glucose Levels in an Aging Population
Completed · Not applicable
Conditions studied: Aging, Cardiovascular Diseases, Glucose Intolerance
In brief
Physical inactivity is known to increase post meal blood sugar levels in young, active populations. However, how quickly this may occur in active, older adults is not clear. Further, the relationship between blood vessel health and blood sugar disturbances which occur to acute physical inactivity is not clear. It is unknown if impairments in blood vessel function precede increases in blood sugar levels that occurs with inactivity in an aging population. This study aims to determine if short term reductions in physical activity impair blood vessel health and blood glucose control to a greater extent in an aging population compared to a young population. The investigators hypothesize that 3 days of reduced physical activity will result in impaired blood vessel function and glycemic control in an aged population.
Key facts
- Study ID
- NCT04812392
- Run by
- Leryn Reynolds
- People needed
- 20
- Starts
- 2021-04-01
- Expected to finish
- 2022-01-30
- Last updated by the study team
- 2026-03-04
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- 55 years and older, 18-40 years old
- Healthy, physically active, performing at least 90 min/week of physical activity
- Free of physical limitations that may interfere with alterations in daily physical activity levels
You may not qualify if…
- Physician diagnosed metabolic disease, HIV, hepatitis, or tuberculosis.
- Body weight change of greater than 5% within the previous 2 months
- Smoking within the previous 2 months.
- Taking medications that alter blood glucose levels
Where it is running
- Old Dominion University — Norfolk, Virginia, United States
Full record on ClinicalTrials.gov
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