Effectiveness of a CBT-based mHealth Intervention Targeting MOUD Retention, Adherence, and Opioid Use

Completed · Not applicable

Conditions studied: Opioid-use Disorder

In brief

The focus of this study is to examine the effectiveness of imFREE relative to mHealth ED in facilitating treatment retention and adherence and reducing opioid use among adults with OUD initiating BUP treatment. There are two specific aims: (1) to test the effectiveness of imFREE, delivered in conjunction with medical management with buprenorphine (imFREE + MM), relative to mHealth ED + MM, in facilitating buprenorphine treatment retention and adherence in a population of individuals with OUD initiating MM (N=200). (2) To evaluate the cost-effectiveness of imFREE.

Key facts

Study ID

NCT04808479

Run by

University of California, Los Angeles

People needed

210

Starts

2019-12-10

Expected to finish

2026-06-15

Last updated by the study team

2026-07-07

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age > 18
• DSM-5 diagnosis of OUD
• no more than 2 weeks from the date of BUP induction
• able to read and comprehend English at the 6th grade level (determined by REALM)
• able to provide informed consent
• presently owns a mobile phone that can send and receive text messages

You may not qualify if…

• Participants must not have:
• Life threatening or unstable medical illness requiring treatment or making participation difficult
• Dependence on alcohol or other illicit substances for which medical detoxification is imminently needed
• Presence of acute psychiatric symptoms warranting intensive treatment or hospitalization (e.g., acute suicidality or mania).

Where it is running

• Tarzana Treatment Center — Tarzana, California, United States

Full record on ClinicalTrials.gov

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