Association of Periodontal Inflammation on Immune Response in Wound Healing

Recruiting now

Conditions studied: Inflammation of Mouth

In brief

Subjects who are in need of extraction of a posterior tooth will be recruited for this study. Prior to extraction, periodontal clinical markers of inflammation, body-mass index and dental radiographs will be measured/taken. The posterior tooth will be atraumatically extracted and a small soft tissue biopsy of the extraction site will be taken. At the two week follow-up, sutures will be removed and another small biopsy of soft tissue will be taken. Subjects will be seen again at 3 months for a final collection of clinical data and radiographs.

Key facts

Study ID

NCT04805320

Run by

University of Nebraska

People needed

25

Starts

2021-09-01

Expected to finish

2026-07-01

Last updated by the study team

2025-12-10

Who can join

Age: 21 and older, up to 70. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• non-restorable posterior tooth (molar/premolar) in need of extraction

You may not qualify if…

• systemic disease that effects inflammation

Where it is running

• University of Nebraska, College of Dentistry — Lincoln, Nebraska, United States (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.