A Study to Evaluate the Efficacy and Safety of Vonoprazan Compared to Placebo in Participants With Symptomatic Non-Erosive Gastroesophageal Reflux Disease
Completed · Phase 2 · Has a placebo group
Conditions studied: Non-Erosive Gastro-Esophageal Reflux Disease, Heartburn
In brief
The primary objectives of this study are to assess the efficacy of vonoprazan (10 mg, 20 mg, and 40 mg On-Demand) compared to placebo (On-Demand) in relief of episodic heartburn over 6 weeks in participants with symptomatic non-erosive gastroesophageal reflux disease (NERD), and to assess the safety of vonoprazan (10 mg, 20 mg, and 40 mg On-Demand) compared to placebo (On-Demand) in participants with symptomatic NERD.
Key facts
- Study ID
- NCT04799158
- Run by
- Phathom Pharmaceuticals, Inc.
- People needed
- 458
- Starts
- 2021-03-25
- Expected to finish
- 2022-01-17
- Last updated by the study team
- 2023-01-04
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- North Alabama Research Center LLC — Athens, Alabama, United States
- Medical Affiliated Research Center Inc — Huntsville, Alabama, United States
- Elite Clinical Studies, LLC — Phoenix, Arizona, United States
- Del Sol Research Management - Clinedge — Tucson, Arizona, United States
- Preferred Research Partners - ClinEdge — Little Rock, Arkansas, United States
- Arkansas Gastroenterology — North Little Rock, Arkansas, United States
- GW Research, Inc — Chula Vista, California, United States
- eStudySite — Chula Vista, California, United States
- Paragon Rx Clinical — Garden Grove, California, United States
- OM Research LLC — Lancaster, California, United States
- Medical Associates Research Group, Inc. — San Diego, California, United States
- Paragon Rx Clinical, Inc. — Santa Ana, California, United States
- Western States Clinical Research Inc — Wheat Ridge, Colorado, United States
- Imagine Research of Palm Beach County — Boynton Beach, Florida, United States
- Riverside Clinical Research — Edgewater, Florida, United States
- Nature Coast Clinical Research — Inverness, Florida, United States
- ENCORE Borland-Groover Clinical Research — Jacksonville, Florida, United States
- ClinCloud — Maitland, Florida, United States
- G. Medical Center — Orlando, Florida, United States
- Advanced Gastroenterology Associates, LLC — Palm Harbor, Florida, United States
- Clinical Research Center of Florida — Pompano Beach, Florida, United States
- Precision Clinical Research, LLC — Sunrise, Florida, United States
- Guardian Angel Research Center — Tampa, Florida, United States
- Florida Medical Clinic, LLC Clinical Research Division — Zephyrhills, Florida, United States
- Pinnacle Research Group — Anniston, Alabama, United States
Full record on ClinicalTrials.gov
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