Pathogenicity of B and CD4 T Cell Subsets in Multiple Sclerosis

Recruiting now · Not applicable

Conditions studied: Multiple Sclerosis, Clinically Isolated Syndrome

In brief

The study aims at identifying the type of B and CD4 T cell subsets with pathogenic properties in the different clinical forms of multiple sclerosis. This research might open new therapeutic approaches for the treatment of multiple sclerosis particularly progressive MS.

Key facts

Study ID

NCT04798651

Run by

University Hospital, Bordeaux

People needed

150

Starts

2021-09-30

Expected to finish

2026-09-01

Last updated by the study team

2026-02-03

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• male or female subjects ;
• Age ≥ 18 years;
• subjects with MS defined by 2010 revised McDonald criteria or presenting a clinical isolated syndrome;
• patients for which a blood draw and / or lumbar puncture to collect CSF is performed for diagnostic or therapeutic purpose;
• affiliated to an health insurance system;
• and who agree to participate in the study.

You may not qualify if…

• Pregnant or breastfeeding women,
• patient concerned by articles L 1121-5 to L 1121-8 (persons deprived of their liberty by a judicial or administrative decision, minors, persons of legal age who are the object of a legal protection measure or unable to express their consent)

Where it is running

• CHU de Bordeaux - service de neurologie — Bordeaux, France (enrolling)

Full record on ClinicalTrials.gov

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