Underlying Mechanisms of Obesity-induced Obstructive Sleep Apnea

Completed

Conditions studied: Obstructive Sleep Apnea, Obesity

In brief

Obesity is a common risk factor for the development of obstructive sleep apnea. However, not all subjects with obesity develop obstructive sleep apnea. This study will attempt to determine the mechanistic drivers between obesity and obstructive sleep apnea.

Key facts

Study ID

NCT04793334

Run by

Brandon Nokes

People needed

106

Starts

2021-03-20

Expected to finish

2025-05-31

Last updated by the study team

2026-02-27

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• - Men and women
• Ages >= 18-65 years old
• BMI 35 kg/m2--and above
• Scheduled for sleeve gastrectomy (bariatric surgery)

You may not qualify if…

• Any cardiovascular, pulmonary or renal disease other than well-controlled hypertension or asthma.
• Pregnancy
• Currently smoking
• Any respiratory disorder other than OSA or well controlled asthma
• contraindication to MRI

Where it is running

• UCSD - Altman Clinical Research Institute (ACTRI) — La Jolla, California, United States

Full record on ClinicalTrials.gov

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