Cognitive Fitness for Depression in Older Adults

Completed · Not applicable

Conditions studied: Depression Mild, Depressive Disorder, Major, Mild Cognitive Impairment

In brief

This research is being done to determine if computerized administered cognitive fitness activities will improve thinking and depression in older depressed adults who are being treated with antidepressants. The investigators are also interested in whether participating in the treatment will result in changes to brain activity measured with magnetic resonance imaging (MRI).

Key facts

Study ID

NCT04790630

Run by

UConn Health

People needed

38

Starts

2020-11-15

Expected to finish

2024-10-15

Last updated by the study team

2026-04-29

Who can join

Age: 60 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• ability to read and write in English
• current major or mild depression despite ongoing treatment
• under the care of a physician who prescribes medication for depression
• currently treated with an antidepressant for at least 8 weeks

You may not qualify if…

• psychosis
• other psychiatric disorders (except personality \& generalized anxiety disorders)
• substance use disorders in the prior year
• clinical diagnosis of dementia
• neurological disorders (e.g., stroke, epilepsy, brain injury with loss of consciousness > 30 minutes, brain tumors, demyelinating diseases)
• corrected visual acuity < 20/70 or color blindness

Where it is running

• UConn Health — Farmington, Connecticut, United States

Full record on ClinicalTrials.gov

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