T Cell Profiling in Patients With Multiple Sclerosis

Withdrawn before enrolling

Conditions studied: Multiple Sclerosis

In brief

The goal of this research study is to to learn more about the body's immune response in patients with multiple sclerosis (MS). In MS, the body's immune cells mistakenly attack an important part of the nerves of the brain and spinal cord. The immune cells responsible for attacking the nerves in MS patients is primarily the T cells. A marker was recently discovered that might specifically identify these damaging T cells from all other T cells in the body. Understanding which T cells cause the damage in MS patients and understanding more about these specific T cells may help doctors better understand how MS occurs and could possibly prevent MS in the future.

Key facts

Study ID

NCT04789551

Run by

Boston Children's Hospital

People needed

0

Starts

2025-12-01

Expected to finish

2026-12-01

Last updated by the study team

2026-06-02

Who can join

Age: 13 and older, up to 20. Sex: any. Healthy volunteers: not accepted.

You may not qualify if…

• Have an active infection
• Take T cell modulating drugs
• Control Group Inclusion criteria -scheduled for elective surgery
• without any immunological diseases. Exclusion criteria
• Have an active infection.

Where it is running

• Boston Children's Hopsital — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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