Coronary CT Angio Evaluating Graft Patency in ACS Patients Treated With DAPT or Single ASA After CABG (CoCAP)

Recruiting now

Conditions studied: Acute Coronary Syndrome, Coronary Bypass Stenosis

In brief

The purpose of this study is to compare the presence of graft patency in single aspirin vs dual anti platelet therapy (DAPT) treatment including ticagrelor in patients with acute coronary syndrome (ACS) treated with coronary artery bypass surgery (CABG). Follow up time is 12-36 months postoperatively and the patency will be evaluated with coronary computed tomography angiography (CCTA)

Key facts

Study ID

NCT04783701

Run by

University Hospital, Linkoeping

People needed

360

Starts

2021-05-17

Expected to finish

2026-03-15

Last updated by the study team

2025-12-19

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Previously included in TACSI-trial

You may not qualify if…

• Highly irregular heart rhythm (i.e. atrial fibrillation)
• Chronic kidney disease with estimated glomerular filtration rate (eGFR) <45ml/min/1,73m2
• Body weight >120 kg
• Previous severe allergic reaction (i.e. anaphylactic reaction) to iodine-based contrast agents
• Not able to communicate
• Not willing to participate

Where it is running

• University Hospital Linköping — Linköping, Östergötland County, Sweden (enrolling)
• Department of Heart Disease, Haukeland University Hospital — Bergen, Norway
• St Olavs University Hospital — Trondheim, Norway
• Department of Molecular and Clinical Medicine, Wallenberg Laboratory, Institute of Medicine — Gothenburg, Sweden
• Dep of Vascular and Thoracic Surgery — Örebro, Sweden
• Department of Cardiothoracic Surgery Karolinska University Hospital — Stockholm, Sweden

Full record on ClinicalTrials.gov

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