Effects of Auditory Stimulation on Sleep and Memory in Schizophrenia
Running, not enrolling · Not applicable · Has a placebo group
Conditions studied: Schizophrenia
In brief
The investigators will test the hypothesis that auditory stimulation (playing quiet sounds during sleep) can normalize brain activity during sleep and improve memory in patients with schizophrenia. The investigators will do this by measuring sleep and memory performance under two conditions separated by one week: receiving auditory stimulation during sleep and not receiving auditory stimulation during sleep. The investigators will study healthy subjects and outpatients with schizophrenia.
Key facts
- Study ID
- NCT04783571
- Run by
- Massachusetts General Hospital
- People needed
- 70
- Starts
- 2020-04-13
- Expected to finish
- 2027-12-31
- Last updated by the study team
- 2026-05-13
Who can join
Age: 18 and older, up to 50. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- For healthy controls:
- Male and female subjects
- 18-50 years of age
- Proficient in English
- For schizophrenia patients:
- Male and female schizophrenia outpatients
- 18-50 years of age
- Proficient in English
- Able to give informed consent
You may not qualify if…
- Pregnant females
- Current use of psychotropic medications (healthy controls only)
- A history of head injury resulting in prolonged loss of consciousness or other neurological sequelae
- IQ <85
- Neurological disorder (including seizure disorder)
- Significant hearing or vision loss
- Current substance abuse or dependence (nicotine abuse or dependence is not exclusionary)
- Any unstable chronic medical condition that affects sleep
- Diagnosed sleep disorder
Where it is running
- Massachusetts General Hospital — Boston, Massachusetts, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.