Prevention of Obesity in Infants of Overweight and Obese Women
Completed · Not applicable
Conditions studied: Infant Obesity
In brief
Maternal and childhood obesity have dramatically increased and continue to present a significant health problem. Studies show that offspring of overweight (body mass index, BMI \>25-29.9) and obese (BMI ≥30) women are at increased risk of newborn and age 1-year adiposity, and infant adiposity predicts childhood and adult obesity. The investigators hypothesize that infants of overweight/obese (OW/OB) mothers have both relative hyperphagia and are provided human milk with increased caloric composition, leading to obesity. The investigators propose an intervention study to calibrate milk or formula intake in infants of OW/OB mothers so as to avoid overweight infants at 6 months of age.
Key facts
- Study ID
- NCT04782063
- Run by
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
- People needed
- 60
- Starts
- 2022-01-01
- Expected to finish
- 2024-05-30
- Last updated by the study team
- 2025-11-20
Who can join
Age: 16 and older, up to 50. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- Breast Milk Calibration Study: Study women (pre-pregnant BMI 25-29.9 and ≥30) who are providing exclusive human milk via pumping and bottle (50%/50% male/female) will be recruited at the 3-6 week postpartum visit.
- Formula Milk Calibration Study: Study women (pre-pregnant BMI 25-29.9 and ≥30) who are providing formula via bottle (50%/50% male/female) will be recruited at the 3-6 week postpartum visit.
You may not qualify if…
- Breast Milk Calibration Study: breast implants, prior breast surgery, flat/ inverted nipples, tongue-tie or low birth weight infants.
- Formula Milk Calibration Study: low birth weight infants.
Where it is running
- Penn State College of Medicine — Hershey, Pennsylvania, United States
Full record on ClinicalTrials.gov
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