Use of Physiology to Evaluate Procedural Result After PCI CTO

Recruiting now · Not applicable

Conditions studied: Percutaneous Coronary Revascularisation, Complex Coronary Lesion

In brief

ULTRA-CTO is a prospective multicentre non-randomised investigator-initiated trial designed to enrol 200 subjects with an indication for percutaneous coronary intervention (PCI) of chronic total occluded (CTO) coronary artery. The main objective of the study is to assess the predictive value of post-PCI resting full-cycle ratio (RFR) and fractional flow reserve (FFR) with regard to Fractional flow reserve (SSR) in CTO patients.

Key facts

Study ID

NCT04780971

Run by

Isala

People needed

200

Starts

2021-07-21

Expected to finish

2026-06-01

Last updated by the study team

2025-02-19

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 18 years and older.
• Angiographically successful PCI CTO without any remaining lesion at least 30% proximal to the stented segment.
• Possibility to perform physiologic measurements and OCT of sufficient quality.
• Patients willing and capable to provide written informed consent.

You may not qualify if…

• Contra-indication for adenosine.

Where it is running

• Isala — Zwolle, Netherlands (enrolling)
• Radboud UMC — Nijmegen, Netherlands

Full record on ClinicalTrials.gov

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