Random Noise Stimulation to Enhance Cortical Drive & Improve Hand Function
Completed · Not applicable · Has a placebo group
Conditions studied: Spinal Cord Injuries, Tetraplegia, Cervical Spinal Cord Injury
In brief
Cervical spinal cord injury (SCI) results in hand and arm function impairments and decreased independence in performance of daily activities such as bathing, eating, dressing, writing, or typing. Recent approaches that involve the application of non-invasive brain stimulation have the potential to strengthen the remaining connections between the brain and the spinal cord for improved hand function. Combining brain stimulation with performing upper limb functional tasks may further increase the ability of individuals with tetraplegia to use their hands. The purpose of this study is to investigate if "random noise", a special type of brain stimulation that most people cannot feel, can be used to enhance upper limb function in individuals with spinal cord injury. Specifically, the investigators will examine if a combined treatment protocol of random noise and fine motor training results in greater improvements in motor and sensory hand function compared to fine motor training alone.
Key facts
- Study ID
- NCT04777149
- Run by
- Shepherd Center, Atlanta GA
- People needed
- 19
- Starts
- 2021-04-12
- Expected to finish
- 2022-08-10
- Last updated by the study team
- 2022-10-26
Who can join
Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Spinal Cord Injury level above C8
- ASIA Impairment Scale (AIS) classification level: C, D
- Time since injury: ≥ 1 year
- Active intrinsic hand muscles in at least one UE
- Active extrinsic hand muscles in both UE
- Ability to follow multiple step commands
- Ability to communicate pain or discomfort
- Willingness to participate in testing
- Ability to obtain informed consent
You may not qualify if…
- Implanted metallic device in the head and/ or pacemaker
- History of seizures
- History of severe headaches
- Severe contractures of UE that would limit participation in FTP
- Prior tendon or nerve transfer surgery
- Received Botulinum toxin injection in the tested UE in the last 3 months
- Pregnancy
Where it is running
- Shepherd Center — Atlanta, Georgia, United States
Full record on ClinicalTrials.gov
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