Improving Diagnostic Standards in Dysphagia
Completed
Conditions studied: Dysphagia
In brief
The purpose of this research is to understand the normal function of swallowing and respiratory muscles in order to establish normal parameters. This will allow us to compare normal physiology and function of swallowing and breathing muscles to people with a medical history that would put them at risk for a swallowing problem. Our goal is to identify the best tests that can be quickly and easily administered to accurately detect swallowing impairment in adults. Involvement is limited to a single 2-hour evaluation.
Key facts
- Study ID
- NCT04773184
- Run by
- University of Florida
- People needed
- 46
- Starts
- 2021-04-27
- Expected to finish
- 2023-09-23
- Last updated by the study team
- 2024-01-17
Who can join
Age: 18 and older, up to 90. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Adults aged 18-90.
- No history of stroke, head and neck cancer or other disorder that might contribute to a swallowing impairment.
- No COVID-19 symptoms within the past 14 days, nor has been around someone testing positive for COVID-19 in the past 14 days.
- Not pregnant.
- No allergies to barium.
You may not qualify if…
- Individuals under the age of 18 or over the age of 90.
- History of stroke, head and neck cancer or other disorder that might contribute to a swallowing impairment.
- Within the past 14 days, individuals with COVID-19 symptoms or a positive COVID-19 test, or who have been exposed to someone with confirmed COVID-19.
- Pregnant women.
- Individuals with allergies to barium.
- Disordered Cohort:
- 132 individuals with an underlying condition documented to lead to dysphagia will be enrolled in this study.
- Inclusion criteria:
- Adult participants aged between 18 and 90 years.
- Confirmed medical diagnosis associated with an increased risk of dysphagia including but are not limited to: head and neck cancer, neurologic (e.g., stroke, traumatic brain impairment), neurodegenerative (e.g., Parkinson's disease, amyotrophic lateral sclerosis), neuromuscular disorders (e.g., myotonic dystrophy, Pompe disease, inclusion body myositis) rheumatologic diseases (e.g., dermatomyositis, inclusion body myositis, scleroderma), chronic respiratory illnesses (e.g., chronic obstructive pulmonary disease), structural (e.g., mass or trauma to the upper aerodigestive tract) and iatrogenic conditions (e.g., post-surgical such as anterior cervical discectomy/fusion or cardiac, post-radiation treatment to the upper aerodigestive tract).
- No COVID-19 symptoms within the past 14 days, nor has been around someone testing positive for COVID-19 in the past 14 days.
- Not Pregnant.
- No allergies to barium.
- Exclusion criteria:
- Individuals under the age of 18 or over the age of 90
- Within the past 14 days, individuals with COVID-19 symptoms or a positive COVID-19 test, or who have been exposed to someone with confirmed COVID-19.
- Pregnant women.
- Individuals with allergies to barium.
Where it is running
- University of Florida Health — Gainesville, Florida, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.