Detection of Small Fiber Neuropathy Using Skin Properties

Recruiting now

Conditions studied: Small Fiber Neuropathy

In brief

Small fiber neuropathy affects millions of peoples worldwide. The neuropathy is causing disabling burning pain and dysautonomia such as dizziness with standing, brain fog, fatigue, constipation, too much or too little sweating. The detection of nerve damage is complicated and not widely available; it requires either skin biopsy or specialized equipment and training. This project utilizes the mathematical processing of skin pictures for the purpose to extract the statistical features related to loss of small fibers. This approach can improve the availability of diagnosis of small fiber neuropathy.

Key facts

Study ID

NCT04759443

Run by

Brigham and Women's Hospital

People needed

400

Starts

2021-07-01

Expected to finish

2027-02-01

Last updated by the study team

2025-02-06

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients with age 18 year or older
• Patients that sign the informed consent form to participate in this study
• Patients completed the autonomic testing with skin biopsies

You may not qualify if…

• Patients with significant hairs at the legs that will cover the skin
• Any dermatological disorder that can affect the skin composition
• The use of skin lotion

Where it is running

• Brigham and Women's Faulkner Hospital — Boston, Massachusetts, United States (enrolling)

Full record on ClinicalTrials.gov

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