Remote Monitoring in Progressive Supranuclear Palsy (PSP)
Starting soon
Conditions studied: Progressive Supranuclear Palsy, Parkinson Disease, MSA - Multiple System Atrophy
In brief
This is a single-arm, longitudinal, observational study on the use of wearable sensors and digital health technology to measure fall frequency and motor, speech, and cognitive function in patients with PSP over the course of approximately one year. Participants will perform supervised remote assessments monthly and in-person assessments approximately every 6 months.
Key facts
- Study ID
- NCT04753320
- Run by
- Massachusetts General Hospital
- People needed
- 85
- Starts
- 2026-09-01
- Expected to finish
- 2028-12-01
- Last updated by the study team
- 2026-07-29
Who can join
Age: 18 and older, up to 89. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Clinical diagnosis of possible or probable PSP phenotype as defined by the 2017 MDS criteria, clinical diagnosis of at least probable PD as defined by the 2015 MDS criteria, or clinical diagnosis of at least probable MSA as defined by the 2022 MDS criteria, or healthy controls.
- Male or female, aged 18 to 89 years, inclusive.
- Fluent in reading and speaking English.
- Capable of providing informed consent based on the investigator's judgment.
- Able to comply with the protocol based on the investigator's judgment.
- Able to walk 10 feet unassisted.
- With access to a caregiver who is able to assist with all study-related procedures.
You may not qualify if…
- Any neurological, medical, or psychiatric condition that would preclude participation in study activities based on the investigator's judgment.
- A history of frequent falls defined as more than 5 falls/month or requirement of a walker to ambulate safely.
Where it is running
- Johns Hopkins — Baltimore, Maryland, United States
- Massachusetts General Hospital — Boston, Massachusetts, United States
Full record on ClinicalTrials.gov
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