Positive Pressure Treadmill Walking for Individuals With Knee Pathology

Status unconfirmed · Not applicable

Conditions studied: Knee Osteoarthritis

In brief

Our goal is to compare the serum biomarker changes of joint disease that occur in response to partially off-loaded (50%) walking exercise to regular (100%) walking exercise while on a Lower Body Positive Pressure (LBPP) treadmill. Secondly we are determining the relationship between changes in the concentration of these serum biomarkers and participant reported knee pain while walking on a LBPP treadmill.

Key facts

Study ID

NCT04747444

Run by

Shirley Ryan AbilityLab

People needed

30

Starts

2019-06-01

Expected to finish

2021-09-01

Last updated by the study team

2021-02-10

Who can join

Age: 50 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age > 50 years
• Diagnosis of unilateral or bilateral knee osteoarthritis
• Clinical AND/OR radiographic knee osteoarthritis.

You may not qualify if…

• Age < 50 years
• History of lower extremity total joint arthroplasty
• Current cardiovascular disease or hypertension that is uncontrolled
• History of neurological disorder that effects lower extremity function (i.e., stroke, peripheral neuropathy, multiple sclerosis, Parkinson's disease)
• Current ankle or hip pain
• Currently pregnant for female participants
• Weight over 400 lbs (181.4 kg), height less than 4'8" (142 cm) or over 6'4" (193 cm), 18.5" (47 cm) hip width, or 58" (147 cm) hip circumference

Where it is running

• Shirley Ryan AbilityLab — Chicago, Illinois, United States (enrolling)

Full record on ClinicalTrials.gov

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