A Study of Ociperlimab With Tislelizumab Compared to Pembrolizumab in Participants With Untreated Lung Cancer
Stopped early · Phase 3 · Has a placebo group
Conditions studied: Non-small Cell Lung Cancer, NSCLC
In brief
The purpose of this study is to evaluate the efficacy and safety of ociperlimab + tislelizumab compared with that of pembrolizumab in adults with high levels of programmed cell death ligand-1 (PD-L1), locally advanced/recurrent or untreated metastatic non-small cell lung cancer (NSCLC).
Key facts
- Study ID
- NCT04746924
- Run by
- BeiGene
- People needed
- 669
- Starts
- 2021-05-24
- Expected to finish
- 2026-03-18
- Last updated by the study team
- 2026-05-12
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Valkyrie Clinical Trials — Los Angeles, California, United States
- Ocala Oncology Center Pl Dba Florida Cancer Affiliates Ocala — Ocala, Florida, United States
- Advent Health Cancer Institute — Orlando, Florida, United States
- Goshen Center For Cancer Care — Goshen, Indiana, United States
- Baptist Health Lexington — Lexington, Kentucky, United States
- University Medical Center New Orleans West Jefferson Medical Center — New Orleans, Louisiana, United States
- Metro Minnesota Community Oncology Research Consortium (Mmcorc) — Saint Paul, Minnesota, United States
- West Penn Hospital — Pittsburgh, Pennsylvania, United States
- Centro Medical Austral — Buenos Aires, Argentina
- Centro Para La Atencion Del Paciente Oncologico (Caipo) — San Miguel de Tucumán, Argentina
- Concord Repatriation General Hospital — Concord, New South Wales, Australia
- Northern Cancer Institute — St Leonards, New South Wales, Australia
- Calvary Mater Newcastle — Waratah, New South Wales, Australia
- Pindara Private Hospital — Benowa, Queensland, Australia
- The Prince Charles Hospital — Chermside, Queensland, Australia
- Mater Cancer Care Centre — South Brisbane, Queensland, Australia
- John Flynn Private Hospital — Tugun, Queensland, Australia
- Lyell McEwin Hospital — Elizabeth Vale, South Australia, Australia
- Ballarat Health Services — Ballarat, Victoria, Australia
- Monash Health — Clayton, Victoria, Australia
- Western Health Sunshine Hospital — St Albans, Victoria, Australia
- St John of God, Murdoch — Murdoch, Western Australia, Australia
- Instituto Dor de Pesquisa E Ensino Distrito Federal — Brasília, Brazil
- Hospital Evangelico de Cachoeiro de Itapemirim — Cachoeiro de Itapemirim, Brazil
- Providence Medical Foundation St Jude Heritage Healthcare — Fullerton, California, United States
Full record on ClinicalTrials.gov
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