Study to Evaluate the Efficacy and Safety of Remdesivir in Participants With Severely Reduced Kidney Function Who Are Hospitalized for Coronavirus Disease 2019 (COVID-19)
Stopped early · Phase 3 · Has a placebo group
Conditions studied: COVID-19
In brief
The primary objective of this study is to evaluate whether remdesivir (RDV, GS-5734™) reduces the composite risk of death or invasive mechanical ventilation (IMV) through Day 29 in participants with severely reduced kidney function who are hospitalized for coronavirus disease 2019 (COVID-19).
Key facts
- Study ID
- NCT04745351
- Run by
- Gilead Sciences
- People needed
- 249
- Starts
- 2021-03-31
- Expected to finish
- 2022-05-24
- Last updated by the study team
- 2023-05-12
Who can join
Age: 12 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- UAB Hospital — Birmingham, Alabama, United States
- Pulmonary Associates of Mobile, P.C. — Mobile, Alabama, United States
- St. Joseph Hospital Eureka — Eureka, California, United States
- Hoag Memorial Hospital Presbyterian, 16200 Sand Canyon Ave — Irvine, California, United States
- Hoag Memorial Hospital Presbyterian — Newport Beach, California, United States
- Sutter Medical Center Sacramento — Sacramento, California, United States
- Torrance Memorial Medical Center — Torrance, California, United States
- MedStar Health Research Institute — Washington D.C., District of Columbia, United States
- George Washington Medical Faculty Associates — Washington D.C., District of Columbia, United States
- North Florida/ South Georgia Veterans Health System — Gainesville, Florida, United States
- Mayo Clinic Florida — Jacksonville, Florida, United States
- Genesis Clinical Research — Tampa, Florida, United States
- Northwestern Medicine Central DuPage Hospital — Winfield, Illinois, United States
- Baptist Health Lexington — Lexington, Kentucky, United States
- Tulane Medical Center, 2000 Canal St. — New Orleans, Louisiana, United States
- Tulane Medical Center — New Orleans, Louisiana, United States
- Wake Forest University Health Sciences — Bethesda, Maryland, United States
- Holy Cross Hospital, 19801 Observation Dr — Germantown, Maryland, United States
- Holy Cross Hospital — Silver Spring, Maryland, United States
- Massachusetts General Hospital — Boston, Massachusetts, United States
- Newton-Wellesley Hospital — Newton, Massachusetts, United States
- St. Clair Nephrology Research — Grosse Pointe Woods, Michigan, United States
- G.V. (Sonny) Montgomery VAMC — Jackson, Michigan, United States
- Mayo Clinic Hospital — Rochester, Minnesota, United States
- St. Vincent's Health System — Birmingham, Alabama, United States
Full record on ClinicalTrials.gov
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