Real-Time Levodopa Level Monitoring in Parkinson Disease

Recruiting now · Not applicable

Conditions studied: Parkinson Disease

In brief

This project aims to develop a minimally invasive sensor device to monitor levodopa levels in real time. We will test the accuracy, tolerability, and safety of this device in people with Parkinson disease.

Key facts

Study ID

NCT04735627

Run by

University of California, San Diego

People needed

20

Starts

2021-12-07

Expected to finish

2028-02-01

Last updated by the study team

2025-02-11

Who can join

Age: 40 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Participants must meet the Movement Disorders Society (MDS) diagnostic criteria for clinically established Parkinson disease.
• Able to provide signed informed consent (in English or Spanish)
• Mild, moderate, or severe Parkinson disease, able to ambulate (Hoehn and Yahr stages I-IV)
• Taking instant release oral carbidopa/levodopa therapy
• Either not taking, or on stable doses of any of the following antiparkinsonian medications: dopamine agonists, monoamine oxidase B (MAO-B) inhibitors or catecholamine O-methyl transferase (COMT) inhibitors

You may not qualify if…

• Other neurological conditions including but not limited to stroke, dementia (including Parkinson disease dementia), or traumatic brain injury
• Co-existent major psychiatric disease
• Uncontrolled, active medical conditions (e.g., heart, kidney, or liver failure, diabetes, etc.)
• Status post deep brain stimulation (DBS) device placement
• Any other condition, that in the opinion of the investigators, would place the participant at risk.

Where it is running

• University of California San DIego — San Diego, California, United States (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.