Motor Cortical Neuromodulation in Women With Interstitial Cystitis/Bladder Pain Syndrome
Running, not enrolling · Not applicable · Has a placebo group
Conditions studied: Interstitial Cystitis, Bladder Pain Syndrome
In brief
Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) is a common, chronic, and debilitating condition in women. Preliminary evidence suggests that IC/BPS pain can be reduced applying non-invasive repetitive transcranial magnetic stimulation (rTMS) to areas of the brain that regulate pelvic floor muscle activity. However, prior studies have examined rTMS in a very limited sample and have not examined changes in brain or pelvic floor muscle activity to determine the mechanism of rTMS for IC/BPS. This study is designed to directly address these limitations.
Key facts
- Study ID
- NCT04734847
- Run by
- University of Southern California
- People needed
- 50
- Starts
- 2021-06-01
- Expected to finish
- 2026-10-30
- Last updated by the study team
- 2026-06-17
Who can join
Age: 18 and older. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- Be at least 18 years old.
- Be female.
- Have a diagnosis of IC/BPS by the referring physician, with urologic symptoms present a majority of the time during the most recent 3 months
- Screen within standard limits for pelvic pain
You may not qualify if…
- Symptomatic urethral stricture
- On-going neurological conditions affecting the bladder or bowel
- Active auto-immune or infectious disorders
- History of cystitis caused by tuberculosis or radiation or chemotherapies
- History of non-dermatologic cancer
- Current major psychiatric disorders
- Severe cardiac, pulmonary, renal, or hepatic disease
- Conditions or the use of medical devices that are contraindications for either fMRI or rTMS procedures, including pregnancy, seizure disorders, or chronic headaches
Where it is running
- University of Southern California — Los Angeles, California, United States
Full record on ClinicalTrials.gov
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