Alpelisib Plus Olaparib in Platinum-resistant/Refractory, High-grade Serous Ovarian Cancer, With no Germline BRCA Mutation Detected

Stopped early · Phase 3

Conditions studied: Ovarian Cancer

In brief

The objective of this study was to assess the efficacy and safety of the combination of alpelisib and olaparib compared with single agent cytotoxic chemotherapy in patients with platinum resistant or refractory high-grade serous ovarian cancer, with no germline BRCA mutation detected.

Key facts

Study ID
NCT04729387
Run by
Novartis Pharmaceuticals
People needed
358
Starts
2021-07-22
Expected to finish
2026-01-19
Last updated by the study team
2026-06-04

Who can join

Age: 18 and older, up to 100. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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