Neural Correlates of Psychiatric Disorders

Recruiting now

Conditions studied: Psychiatric Disorder, Memory Disorders

In brief

This ClincialTrials.gov record originally corresponded to the protocol approved under IRB # 202370. The study was expanded to include stimulation and recordings approved under new IRB #211037. The participant data originally acquired from IRB# 202370 will be included in this new record: This study seeks to better understand the neural activity underlying neuro cognitive disorders. Resting state local field potential recordings will be collected from medically refractory epilepsy patients implanted with depth electrodes for seizure localization, and metrics of neural activity will be correlated with psychiatric symptoms as measured from questionnaires. Subjects will also participate in neuro cognitive tasks while neural recordings are performed, and/or receive neural stimulation through implanted depth electrodes. A better understanding of disordered neural activity underlying neuropsychiatric disorders may additionally contribute to novel methods for diagnosing, treating, and preventing these diseases.

Key facts

Study ID

NCT04725409

Run by

Vanderbilt University Medical Center

People needed

100

Starts

2021-03-31

Expected to finish

2027-12-01

Last updated by the study team

2026-06-12

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Undergoing SEEG monitoring at Vanderbilt University Medical Center
• At least 18 years of age
• English speaking

You may not qualify if…

• Age <18
• Not able to complete questionnaires (e.g., unable to comprehend instructions or follow directions)

Where it is running

• Vanderbilt University Medical Center — Nashville, Tennessee, United States (enrolling)

Full record on ClinicalTrials.gov

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