Fluid Intake After Hemodialysis

Recruiting now

Conditions studied: Chronic Kidney Disease Requiring Chronic Dialysis, Interdialytic Weight Gain

In brief

Interdialytic weight gain determines how much fluid (ultrafiltration) has to be removed during each hemodialysis session. High ultrafiltration volumes stress the organism and lead to a higher risk of death. Thirst is the main driving factor of interdialytic weight gain, and thirst is mainly driven by salt intake, molecules that increase blood tonicity (such as sugar in diabetics) and fluid loss (such as in dehydration and blood loss). It has been speculated that fluid loss during hemodialysis could increase the sense of thirst immediately following dialysis, but this statement requires further evidence.

Key facts

Study ID

NCT04721652

Run by

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

People needed

20

Starts

2021-02-25

Expected to finish

2026-12-31

Last updated by the study team

2026-05-04

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥ 18 years
• Thrice weekly maintenance hemodialysis
• Willing and able to provide written informed consent

You may not qualify if…

• Diabetes Mellitus
• Residual Urinary Volume > 500 ml/day
• Being able to self-monitor one's body weight and blood pressure

Where it is running

• Adam Linton Unit — London, Ontario, Canada (enrolling)
• Westmount Kidney Care Centre — London, Ontario, Canada (enrolling)

Full record on ClinicalTrials.gov

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