Corticostriatal Contributions to Parkinson's Disease Cognitive Impairment
Recruiting now · Not applicable
Conditions studied: Parkinson Disease
In brief
The goal of this study is to learn more about the brain activity underlying Parkinson's disease cognitive impairment. The investigators will utilize neural recordings from corticostriatal structures performed during deep brain stimulation surgery to measure neural activity underlying nonmotor symptoms of Parkinson's disease.
Key facts
- Study ID
- NCT04715984
- Run by
- Vanderbilt University Medical Center
- People needed
- 75
- Starts
- 2021-06-02
- Expected to finish
- 2029-08-01
- Last updated by the study team
- 2026-06-12
Who can join
Age: 40 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Scheduled to undergo deep brain stimulation surgery under local anesthesia at Vanderbilt University Medical Center
- Planned clinical electrode trajectory that contacts caudate
- Age greater than or equal to 40
- Diagnosis of Parkinson's disease
- Able to participate in intraoperative testing
- English speaking
You may not qualify if…
- Age less than 40
- Not able to participate in intraoperative testing (for example unable to comprehend instructions or follow directions)
- Movement disorder other than Parkinson's disease
Where it is running
- Vanderbilt University Medical Center — Nashville, Tennessee, United States (enrolling)
Full record on ClinicalTrials.gov
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