Multicomponent Prehabilitation and Outcomes in Elderly Patients With Frailty
Recruiting now · Not applicable
Conditions studied: Old Age; Debility, Digestive Cancer, Surgery, Preoperative Rehabilitation, Nutrition Therapy, Outcomes
In brief
The study is designed to investigate the effect of a multicomponent prehabilitation pathway on early and long-term outcomes in elderly patients with frailty recovering from surgery for digestive cancer.
Key facts
- Study ID
- NCT04715581
- Run by
- Peking University First Hospital
- People needed
- 540
- Starts
- 2021-11-25
- Expected to finish
- 2028-12-01
- Last updated by the study team
- 2025-07-31
Who can join
Age: 65 and older, up to 89. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age ≥65 years but <90 years;
- Scheduled to undergo major surgery for digestive cancer with an expected duration of 2 hours and longer, including cancers of esophagus, stomach, small intestine, colon, rectum, pancreas, liver, and biliary tract;
- Clinical Frailty Scale ≥5;
- Provide written informed consent.
You may not qualify if…
- Preoperative history of schizophrenia, epilepsy, Parkinsonism, or myasthenia gravis;
- Inability to communicate due to coma, profound dementia, or language barrier;
- Inability to participate in preoperative rehabilitation due to paralysis, fracture or other movement disorder;
- Inability to take oral diet due to preoperative gastrointestinal disease or other disease;
- Severe heart dysfunction (left ventricular ejection fraction <30% or New York Heart Association classification IV), severe hepatic dysfunction (Child-Pugh class C), severe renal dysfunction (undergoing dialysis before surgery), or American Society of Anesthesiologists classification of grade 4 or higher;
- Other reasons that are considered unsuitable for study participation.
Where it is running
- Peking University First Hospital — Beijing, Beijing Municipality, China (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.