Comparing the Effects of Different Doses of Dexamethasone to Treat Inpatient COVID-19

Completed · Phase 4

Conditions studied: Covid19

In brief

This open label clinical trial is to evaluate two different doses of dexamethasone on the health outcome using World Health Organization ordinal scale at day 28 in hospitalized patients with COVID-19.

Key facts

Study ID

NCT04707534

Run by

University of Oklahoma

People needed

110

Starts

2021-01-21

Expected to finish

2022-03-04

Last updated by the study team

2024-03-29

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥ 18 years old
• RT-PCR confirmed COVID-19 infection
• Positive pressure ventilation (non-invasive or invasive) or high flow nasal cannula (HFNC) or need supplemental oxygen with oxygen mask or nasal cannula

You may not qualify if…

• Underlying disease requiring chronic corticosteroids
• Severe adverse events before admission, i.e. cardiac arrest;
• Contraindication for corticosteroids;
• Death is deemed to be imminent and inevitable during the next 24 hours
• Recruited in other clinical intervention trial
• Pregnancy
• Patient on judicial protection

Where it is running

• University of Oklahoma Medical Center — Oklahoma City, Oklahoma, United States

Full record on ClinicalTrials.gov

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