Comprehensive Adaptive Multisite Prevention of University Student Suicide

Completed · Not applicable

Conditions studied: Suicide

In brief

Suicide is the 2nd leading cause of death among college students and suicidal ideation and suicide-related behaviors are a frequent presenting problem at college counseling centers (CCCs), which are overburdened. Studies show that some students respond rapidly to treatment, whereas others require considerably more resources. Evidence-based adaptive treatment strategies (ATSs) are needed to address this heterogeneity in responsivity and complexity. ATSs individualize treatment via decision rules specifying how the type and intensity of an intervention can be sequenced based on risk factors, response, or compliance. The purpose of this multisite study is to investigate the effectiveness of four adaptive treatment strategies (ATSs) to treat college students who report suicidal ideation when first seeking services at their college counseling center This multisite study will enroll moderately to severely suicidal college students in the "emerging adulthood" phase (ages 18-25) seeking services at CCCs. This Sequential Multi-Assignment Randomized Trial (SMART) will have two stages of intervention. In Stage 1, 700 participants from four CCCs will be randomized to 4-8 weeks of: 1) a suicide-focused treatment - Collaborative Assessment and Management of Suicidality (CAMS) or 2) Treatment as Usual (TAU). Sufficient responders to either intervention will discontinue services/be stepped down. Non-responders will be re-randomized to one of two Stage 2 higher intensity/dosage intervention options for an additional 4-16 weeks: 1) CAMS (either continued or administered for the first time) or 2) Comprehensive Dialectical Behavior Therapy (DBT), which includes individual therapy, skills group, and phone/text coaching for the clients and peer consultation for the counselors.

Key facts

Study ID

NCT04707066

Run by

Duke University

People needed

227

Starts

2022-10-25

Expected to finish

2024-11-19

Last updated by the study team

2024-11-22

Who can join

Age: 18 and older, up to 25. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Enrolled at the university;
• 18 to 25 years of age;
• Moderate to severe SI over the last two weeks indicated by a score of ³2 on the Counseling Center Assessment of Psychological Symptoms (CCAPS-34) question, "I have thoughts of ending my life" (range is 0 "not at all like me" to 4 "extremely like me"); and
• Agree to video recording of all therapy and assessment sessions.

You may not qualify if…

• Students who are deemed clinically inappropriate to receive services at the CCC by an intake counselor because of imminent risk, severe psychosis, or inability to remain enrolled in school (e.g., academic failure);
• Students being unable to remain on campus long enough to go through the minimum number of sessions for Stage 1 (4 sessions);
• Students who have received services at the CCC within the last three months (i.e., ATSs must be based on a new treatment episode).

Where it is running

• University of Nevada - Reno — Reno, Nevada, United States
• Rutgers University — New Brunswick, New Jersey, United States
• Duke University — Durham, North Carolina, United States
• University of Oregon — Eugene, Oregon, United States

Full record on ClinicalTrials.gov

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