A Study of AMG 757 in Participants With Neuroendocrine Prostate Cancer
Completed · Phase 1
Conditions studied: Neuroendocrine Prostate Cancer
In brief
To evaluate the safety and tolerability of Tarlatamab and will determine the maximum tolerated dose (MTD) or recommended phase 2 dose (RP2D).
Key facts
- Study ID
- NCT04702737
- Run by
- Amgen
- People needed
- 41
- Starts
- 2021-06-10
- Expected to finish
- 2024-07-22
- Last updated by the study team
- 2025-09-12
Who can join
Age: 18 and older. Sex: male. Healthy volunteers: not accepted.
Where it is running
- Mayo Clinic Arizona — Phoenix, Arizona, United States
- University of California at San Francisco Helen Diller Family Comprehensive Cancer Center — San Francisco, California, United States
- Winship Cancer Institute of Emory University — Atlanta, Georgia, United States
- University of Chicago — Chicago, Illinois, United States
- Community Health Network MD Anderson Cancer Center - North — Indianapolis, Indiana, United States
- Washington University — St Louis, Missouri, United States
- Weill Cornell Medical College — New York, New York, United States
- Wake Forest University Health Sciences — Winston-Salem, North Carolina, United States
- The Ohio State University — Columbus, Ohio, United States
- University of Texas MD Anderson Cancer Center — Houston, Texas, United States
- Chris OBrien Lifehouse — Camperdown, New South Wales, Australia
- Peter MacCallum Cancer Centre — Melbourne, Victoria, Australia
- Medizinische Universitaet Graz — Graz, Austria
- Ordensklinikum Linz Elisabethinen — Linz, Austria
- Landeskrankenhaus Salzburg — Salzburg, Austria
- Universitair Ziekenhuis Gent — Ghent, Belgium
- Gustave Roussy — Villejuif, France
- Keio University Hospital — Shinjuku-ku, Tokyo, Japan
- Erasmus Medisch Centrum — Rotterdam, Netherlands
- Hospital Clinic i Provincial de Barcelona — Barcelona, Catalonia, Spain
- Royal Marsden Hospital — Sutton, United Kingdom
Full record on ClinicalTrials.gov
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