Genetic Risks for Childhood Cancer Complications in Switzerland

Recruiting now

Conditions studied: Childhood Cancer, Genetic Predisposition, Late Effect

In brief

The objectives of the GECCOS project are to identify genetic variants associated with complications of childhood cancer using genotype-phenotype association studies. Germline genetic samples and data of the "Germline DNA Biobank for Childhood Cancer and Blood Disorders Switzerland" (BISKIDS) which is included in the Geneva Biobank for Hematology and Oncology in Pediatrics (BaHOP) will be used with clinical data of Swiss childhood cancer patients collected at the Institute of Social and Preventive Medicine in Bern.

Key facts

Study ID

NCT04702321

Run by

University Hospital, Geneva

People needed

6000

Starts

2020-12-01

Expected to finish

2037-12-31

Last updated by the study team

2021-01-13

Who can join

Age: any, up to 21. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Registered in the Swiss Childhood Cancer Registry (SCCR) since 1976; AND
• consented to the BaHOP (host biobank for the BISKIDS Biobanking project); AND
• diagnosed with cancer according to the International Classification of Childhood Cancer, version 3, ICCC-3, or Langerhans cell histiocytosis (LCH) before age 21 years.

You may not qualify if…

• Lacking written consent signed by participant and/ or their legal representative to participate in the BaHOP (where applicable); OR
• died after study participation and declined use of their samples and data after their death in the original consent for BaHOP (as indicated on the BaHOP consent).

Where it is running

• University Hospital of Geneva — Geneva, Switzerland (enrolling)

Full record on ClinicalTrials.gov

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