Remediation Program Via a "Serious Game" for the Cognitive Functions of Multiple Sclerosis Patients

Recruiting now · Not applicable

Conditions studied: Multiple Sclerosis, Memory, Learning

In brief

The main goal of this study is to assess the effectiveness of a cognitive remediation program based on a "serious game" on the information processing speed evolution and the process of learning via episodic memory in multiple sclerosis patients.

Key facts

Study ID

NCT04694534

Run by

Lille Catholic University

People needed

150

Starts

2021-10-08

Expected to finish

2027-03-01

Last updated by the study team

2025-09-04

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Relapsing-remitting or progressive multiple sclerosis people defined according to Mc Donald's criteria revised in 2005
• Age between ≥ 18 and ≤ 65 years old
• Cognitive complaint, with at least one deficient score at the initial neuropsychological examination (<5th percentile of the reference group), one of the scores of which concerns at least one BICAMS test
• Have not had a definite relapse for at least 6 weeks
• Be at least 4 weeks away from a corticosteroid bolus
• Lack of neuroleptic treatment
• Patient with an Internet connection
• Signed informed consent

You may not qualify if…

• Severe cognitive deficit defined by obtaining a deficit score in more than six cognitive processes at the initial neuropsychological assessment.
• Neuropsychological care
• Inability to receive oral and written information
• Inability to use the software (due in particular to motor and / or sensory difficulties),
• Neurological or psychiatric comorbidity, other than MS and anxiodepressive syndrome
• Patient with severe anxiodepressive syndrome (BDI> 27)
• Participation in an interventional study on cognitive functions
• Patient under legal protection, guardianship or curatorship
• Pregnant or breastfeeding women

Where it is running

• CH Arras — Arras, Hauts-de-France, France (enrolling)
• CH LENS — Lens, Hauts-de-France, France (enrolling)
• CHRU — Lille, Hauts-de-France, France (enrolling)
• Saint Vincent hospital — Lille, Hauts-de-France, France (enrolling)
• Saint-Philibert hospital — Lomme, Nord, France (enrolling)
• Charles Nicolle Hospital — Rouen, Normandy, France (enrolling)

Full record on ClinicalTrials.gov

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