Posoleucel (ALVR105, Formerly Viralym-M) for Multi-Virus Prevention in Patients Post-Allogeneic Hematopoietic Cell Transplant
Completed · Phase 2/Phase 3
Conditions studied: Adenovirus Infection, BK Virus Infection, Cytomegalovirus Infections, Epstein-Barr Virus Infections, Human Herpes Virus-6 Infection, JC Virus Infection
In brief
This is a Phase 2 study to evaluate posoleucel (ALVR105, formerly Viralym-M); an allogeneic, off-the-shelf multi-virus specific T cell therapy that targets six viral pathogens: BK virus, cytomegalovirus, adenovirus, Epstein-Barr virus, human herpesvirus 6 and JC virus.
Key facts
- Study ID
- NCT04693637
- Run by
- AlloVir
- People needed
- 26
- Starts
- 2021-01-15
- Expected to finish
- 2023-01-19
- Last updated by the study team
- 2024-05-09
Who can join
Age: 1 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- University of Alabama at Birmingham — Birmingham, Alabama, United States
- City of Hope National Medical Center — Duarte, California, United States
- University of California, San Francisco Medical Center — San Francisco, California, United States
- Childrens National Medical Center — Northwest Rectangle, District of Columbia, United States
- Indiana University Melvin and Bren Simon Cancer Center — Indianapolis, Indiana, United States
- University of Kansas Hospital — Westwood, Kansas, United States
- University of Maryland Medical Center — Baltimore, Maryland, United States
- The Johns Hopkins Hospital — Baltimore, Maryland, United States
- University of Minnesota — Minneapolis, Minnesota, United States
- Children's Mercy Kansas City — Kansas City, Missouri, United States
- Weill Cornell Medical College — New York, New York, United States
- Stony Brook University Hospital Cancer Center — Stony Brook, New York, United States
- Nationwide Children's Hospital — Columbus, Ohio, United States
- Children's Medical Center Dallas — Dallas, Texas, United States
- University of Virginia — Charlottesville, Virginia, United States
- Fred Hutchinson Cancer Research Center — Seattle, Washington, United States
Full record on ClinicalTrials.gov
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