The Longitudinal Relationship of HU Adherence to HRQOL, Barriers to Adherence and Habit in SCD.
Completed · Not applicable
Conditions studied: Sickle Cell Disease, Sickle B+ Thalassemia, Sickle Beta Zero Thalassemia, Sickle Cell Hemoglobin C
In brief
The primary objective of this study is to better understand factors contributing to variations in hydroxyurea (HU) adherence behavior in adolescents and young adults (AYA) with sickle cell disease (SCD). To meet this objective, the researchers will conduct a prospective cohort study to determine the longitudinal relationship between HU adherence and health-related quality of life (HRQOL) overtime among AYA with SCD. The long-term goal of this research is to promote medication adherence behavior and improve health outcomes in AYA with SCD.
Key facts
- Study ID
- NCT04691323
- Run by
- Ann & Robert H Lurie Children's Hospital of Chicago
- People needed
- 68
- Starts
- 2021-03-02
- Expected to finish
- 2025-05-29
- Last updated by the study team
- 2026-07-31
Who can join
Age: 12 and older, up to 21. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age 12-21 years old
- Any sickle cell disease genotype
- On steady state of hydroxyurea for 2 months
- Own or have access to a smartphone
- Parents of patients that meet the eligibility criteria and are enrolled in the study will be included
You may not qualify if…
- Patients with recent hospitalizations within the past 7 days
Where it is running
- Ann & Robert H Lurie Children's Hospital of Chicago — Chicago, Illinois, United States
Full record on ClinicalTrials.gov
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