Curcumin in Management of Chronic Obstructive Pulmonary Disease

Status unconfirmed · Not applicable · Has a placebo group

Conditions studied: COPD

In brief

In this double-blind, placebo-controlled trial, 120 patients with a diagnosis of COPD will be randomized to receive either a daily curcumin preparation or placebo for 90 days, in addition to the standard of care treatment. The outcomes will be compared between the study arms. No dose escalation will be used.

Key facts

Study ID

NCT04687449

Run by

Danbury Hospital

People needed

120

Starts

2022-01-01

Expected to finish

2023-12-15

Last updated by the study team

2021-07-09

Who can join

Age: 40 and older, up to 89. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Provision of signed and dated informed consent form by the subject.
• Stated willingness to comply with all study procedures and availability for the duration of the study.
• Clinical diagnosis of COPD, defined as having a smoking history of at least 10 pack-years, a ratio of post bronchodilator forced expiratory volume in 1 second [FEV1] to forced vital capacity of <70%, and a post bronchodilator FEV1 of <80% of the predicted value.
• Patient has not had an acute exacerbation of COPD for at least 4 weeks of time of screening.

You may not qualify if…

• Known allergic reactions to components of the study medication
• Use of turmeric as a spice or a dietary supplement within 3 months prior to enrollment
• Treatment with another investigational drug or other intervention at the time of enrollment
• Pregnancy or lactation
• Treatment with any chemotherapy agent, tacrolimus, talinolol, or sulfasalazine (due to the potential drug-drug interactions) at the time of enrolment
• Short-term steroid course received, for any reason, within 4 weeks prior to enrollment
• SGRQ-C is not available on the language preferred by the patient
• Patient is not able to undergo 6-minute walk due to a non-COPD related reason

Where it is running

• Pulmonary and Sleep Medicine clinic — Danbury, Connecticut, United States

Full record on ClinicalTrials.gov

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