A Personalized Surveillance and Intervention Protocol for Duodenal and Gastric Polyposis in Patients With Familial Adenomatous Polyposis

Recruiting now

Conditions studied: Familial Adenomatous Polyposis

In brief

The purpose of this study is to determine the efficacy and safety of a personalized surveillance and intervention protocol for duodenal and gastric polyposis in patients with familial adenomatous polyposis (FAP)

Key facts

Study ID

NCT04677998

Run by

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

People needed

1000

Starts

2020-11-24

Expected to finish

2027-11-01

Last updated by the study team

2026-02-23

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of FAP, at least one of following: genetic diagnosis (proven APC germline mutation) and/or clinical diagnosis (>100 colorectal adenomas in combination with a positive family history of FAP)
• Age 18 years or older

You may not qualify if…

• Endoscopic removal of all polyps with an indication for removal not possible/feasible
• Gastric or duodenal cancer at baseline endoscopy
• Need for surgery

Where it is running

• MD Anderson — Houston, Texas, United States (enrolling)
• Academic Medical Centre — Amsterdam, North Holland, Netherlands (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.