A Pilot Randomized Trial of Polypectomy Techniques for 4-6 mm Colonic Polyps

Completed · Not applicable

Conditions studied: Colon Polyps

In brief

Complete polypectomy is one of the major factors for effectiveness of colonoscopy to prevent colon cancer. Given the prevalence of the 4-6 mm polyp, and the concern about interval cancers at polypectomy sites, there is a clear and significant need to determine which technique(s) are most appropriate for clinical practice. This study was to compare the three commonly used polypectomy techniques in terms of efficacy and efficiency.

Key facts

Study ID: NCT04666194
Run by: Indiana University
People needed: 353
Starts: 2009-09-01
Expected to finish: 2019-10-01
Last updated by the study team: 2021-01-12

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: accepted.

You may qualify if…

Persons undergoing screening, surveillance, or diagnostic colonoscopy who are found to have 1 or more adenomatous colon polyps 4-6 mm in size with Paris morphology of types I or IIa in well-defined segments of the colon.

You may not qualify if…

Inability to provide informed consent
Requirement for long-term anticoagulation or clopidogrel (Plavix)
Known International normalized ratio (INR) ≥ 1.5
Less than satisfactory colon preparation quality
Inability to intubate the cecum or reach the surgical anastomosis in case of cecectomy
Age greater than 75
Inpatient status (acute lower GI bleeding, etc.)
Comorbidity that precludes the need for surveillance
Pregnancy
Already included in the protocol
Pre- solid organ transplantation

Where it is running

Springmill endoscopy center — Carmel, Indiana, United States
Indiana University Hospital — Indianapolis, Indiana, United States
Wishard Memorial Hospital/Eskenazi Health — Indianapolis, Indiana, United States

Full record on ClinicalTrials.gov

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