National Bacterial Meningitis Study in Children and Newborns

Recruiting now

Conditions studied: Meningitis, Children, Only, Pneumococcal Conjugate Vaccine, Meningococcal Vaccines, H. Influenzae Vaccine, Neonatal Infection, Antibiotic Treatment, Case Fatality Rate

In brief

Bacterial meningitis is a major cause of morbidity and mortality in childhood. Antibiotic treatment recommendations are based on epidemiological and susceptibility data. The epidemiology of bacterialméningitis has changed in recent years, mainly owing to widespread use of different conjugate vaccines. The aim of this prospective national survey is to describe epidemiology of bacteria implicated in bacterial meningitis in children.

Key facts

Study ID

NCT04664569

Run by

Association Clinique Thérapeutique Infantile du val de Marne

People needed

10000

Starts

2001-01-01

Expected to finish

2030-01-01

Last updated by the study team

2026-04-28

Who can join

Age: 0 and older, up to 18. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• clinical signs of meningitis, associated with positive cerebrospinal fluid (CSF) culture and/or positive CSF antigen testing (Escherichia coli K1, N. meningitidis serogroups B, A, C, Y and W-135, group B streptococci, Hib, or S. pneumoniae), and/or positive CSF polymerase chain reaction (PCR), and/or positive blood culture with CSF pleocytosis (> 10 cells/µL).
• purpura fulminans

Where it is running

• ACTIV — Créteil, France (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.