Comparing Home, Office, and Telehealth Induction for Medication Assisted Treatment for Opioid Use Disorder

Status unconfirmed · Not applicable

Conditions studied: Opioid-use Disorder, Opioid Dependence

In brief

HOMER is a national study comparing three methods of induction for Medication Assisted Treatment (MAT) for Opioid Use Disorder (OUD); home versus office versus telehealth-based inductions. This study will help determine if certain patient and practice characteristics make patients better candidates for one method over the others. Results will help fill a gap in the evidence around effectively treating OUD with MAT in primary care settings.

Key facts

Study ID

NCT04664062

Run by

University of Colorado, Denver

People needed

303

Starts

2021-05-13

Expected to finish

2026-02-28

Last updated by the study team

2024-04-09

Who can join

Age: 16 and older, up to 89. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Ages 16 and older Identified by their clinician as having opioid dependence and either 1) addiction as defined by DSM-V criteria for OUD and/or 2) chronic pain with long-term, high dose opioid use (greater than one year and morphine equivalent daily dose higher than recommended by the CDC).
• Seeking or agreeing to receive medication assisted treatment (MAT) with buprenorphine or Suboxone (buprenorphine/naloxone).
• Agree to be randomly assigned to undergo MAT induction with one of the three methods being compared in this study.
• home induction (asynchronous, unobserved)
• office induction (synchronous, observed)
• telehealth induction (synchronous phone or video contact, observed) Agree to answer a set of survey questions four times over a nine month period (at the time of enrollment plus 1, 3, and 9 months after starting treatment.

You may not qualify if…

• Hypersensitivity to buprenorphine or naloxone. Are known to have serum aspartate aminotransferase (AST) or alanine aminotransferase (ALT) levels greater than five times normal.
• Are diagnosed with severe, untreated psychiatric illness. Have a preference for one of the MAT induction methods and do not want to be randomly assigned to one.

Where it is running

• University of Colorado — Denver, Colorado, United States
• American Academy of Family Physicians National Research Network — Leawood, Kansas, United States

Full record on ClinicalTrials.gov

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