Efficacy of Targeted Memory Reactivation for Enhancing Exposure Therapy

Completed · Not applicable

Conditions studied: Claustrophobia, Obsessive-Compulsive Disorder, Arachnophobia

In brief

This study evaluates whether a scent applied during exposure therapy and during subsequent sleep will increase the durability of treatment effects for individuals with fear of spiders, contamination, and enclosed spaces.

Key facts

Study ID

NCT04663672

Run by

University of Texas at Austin

People needed

158

Starts

2019-01-29

Expected to finish

2020-03-01

Last updated by the study team

2020-12-11

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Marked anxiety in at least one fear domain (spiders, contamination, or enclosed spaces), as determined by the presence of both:
• self-reported peak anxiety of at least 50 on a 100 point scale in response to two behavioral approach tasks
• self-report measures meeting the following cutoffs for the target fear:
• Fear of Spiders Questionnaire ≥ 50
• Obsessive-Compulsive Inventory-Revised (Washing Subscale) ≥ 4
• Claustrophobia Screener ≥ 2

You may not qualify if…

• Diagnosed sleep disorder
• Current sleep medication usage
• Inability to differentiate two different odors from an indoor scent diffuser
• Current psychotherapy for fear of spiders, snakes, enclosed spaces, or contamination
• Current use of air fresheners, scented candles, or other items with odors related to those used in the study

Where it is running

• Laboratory for the Study of Anxiety Disorders, University of Texas at Austin — Austin, Texas, United States

Full record on ClinicalTrials.gov

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